Nebulizer Testing
At ARE Labs, we are at the forefront of advancing respiratory health through our specialized services in drug formulation and optimization for therapeutic inhalation delivery intended to be administered via nebulizer. Our expertise encompasses a broad spectrum of formulation development and processing, catering to various forms of inhalation therapies intended for nebulizer use including aqueous suspensions, and solutions.
Real-Time Laser Diffraction Particle Sizing: We use state-of-the-art laser diffraction particle sizers for real-time analysis of Active Pharmaceutical Ingredients (API) formulations, ensuring precise particle size distribution.
Cascade Impactors: Our cascade impactor testing provides thorough verification of drug particle size distribution, crucial for consistent and effective aerosol inhalation delivery.
HPLC Verification: Laser diffraction particle sizing does not discriminate between the API and other particles generated during the nebulization process. Through cascade impaction and HPLC analysis we can determine the precise concentration of your API over the entire range of the particle size distribution ensuring your API is being delivered in proper dosages at the optimal particle size.
Nasal Delivery Device Testing
At ARE Labs, we specialize in comprehensive Nasal Delivery Device aerosol testing, delivering essential insights for the development and improvement of nasal drug delivery devices and therapies. Our expert team utilizes state-of-the-art technology to ensure that your products meet the highest standards of efficacy, safety, and quality.
Particle Size Distribution Analysis: Using sophisticated methods, we measure the particle size distribution of aerosolized drugs delivered by nasal delivery devices. This analysis is crucial for ensuring optimal drug deposition in the lungs and effective treatment.
Nasal Drug Delivery Aerosol Testing: We evaluate the particle size and distribution to understand the devices performance in creating a aerosol that can reach targeted areas in the nasal-mucosal region.
Drug Delivery Efficiency: Our tests assess the efficiency of drug delivery, ensuring the maximum amount of medication is delivered to the patient with minimal wastage.
Dry Powder Inhaler Testing
At ARE Labs, we specialize in comprehensive dry powder inhaler (DPI) aerosol testing, delivering essential insights for the development and improvement of DPI devices and therapies. Our expert team utilizes state-of-the-art technology to ensure that your products meet the highest standards of efficacy, safety, and quality.
Particle Size Distribution Analysis: Using sophisticated methods, we measure the particle size distribution of aerosolized drugs delivered by dry powder inhalers. This analysis is crucial for ensuring optimal drug deposition in the lungs and effective treatment.
Powdered Aerosol Testing: We evaluate the particle size and distribution to understand the DPI’s performance in creating a breathable aerosol that can reach targeted areas in the respiratory tract.
Drug Delivery Efficiency: Our tests assess the efficiency of drug delivery, ensuring the maximum amount of medication is delivered to the patient with minimal wastage.
Meter Dose Inhaler Testing
At ARE Labs, we specialize in comprehensive Meter Dose Inhaler (MDI) aerosol testing, delivering essential insights for the development and improvement of MDI devices and therapies. Our expert team utilizes state-of-the-art technology to ensure that your products meet the highest standards of efficacy, safety, and quality.
Delivered Dose Testing: Ensures effective drug delivery with particle sizes under 5μm using cascade impaction and laser diffraction. Key tools include the Anderson Cascade Impactor (ACI) and Next Generation Impactor (NGI), complemented by HPLC analysis for precise API concentration measurement.
Laser Diffraction Particle Size Analysis: Quick and informative for early-stage formulation, utilizing devices like Malvern Spraytec and TSI Aerodynamic Particle Sizers to determine MMAD, GSD, and overall distribution.
Spray Pattern/Plume Geometry: Essential for MDIs and nasal sprays, focusing on plume shape, angle, and dispersion for optimal delivery and bioavailability. Advanced analysis with Proveris SprayView for detailed actuation and imaging.
Formal Product Characterization Studies: Includes comprehensive testing such as simulated lifetime, accelerated aging, and stability assessments to ensure device and formulation integrity under various conditions.
Other Drug Delivery Devices
Other Drug Delivery Devices:
In addition to traditional respiratory drug delivery devices ARE Labs has the experience and expertise to assist in testing new respiratory drug delivery technologies.
Particle Size Distribution Analysis: Using sophisticated methods, we measure the particle size distribution of aerosolized drugs delivered by these medical devices. This analysis is crucial for ensuring optimal drug deposition in the lungs and effective treatment.
Droplet Aerosol Testing: We evaluate the droplet size and distribution to understand the device’s performance in creating a breathable aerosol that can reach the targeted areas in the respiratory tract.
Drug Delivery Efficiency: Our tests assess the efficiency of drug delivery, ensuring the maximum amount of medication is delivered to the patient with minimal wastage.
ARE Labs is at the cutting edge of aerosol applications for delivering medical treatments, particularly in the development of vaccines and gene therapies. Pulmonary or inhalation delivery, a non-invasive method, efficiently targets the respiratory system, offering significant potential for medical science. We specialize in evaluating these treatments and their delivery devices, ensuring optimal deposition in the lungs and nasal mucosal regions.
Particle Size Distribution Analysis: Using sophisticated methods, we measure the particle size distribution of aerosolized vaccines or gene therapy drugs as well as analyze the methods by which they are delivered including nebulizers, meter dose inhalers (MDI), dry powder inhalers (DPI) and others. This analysis is crucial for ensuring optimal drug deposition in the lungs and effective treatment or vaccine administration.
Droplet Aerosol Testing: We evaluate the particle size and distribution to understand the drugs performance in creating a breathable aerosol that can reach targeted areas in the respiratory tract as well as the efficacy of the delivery method itself.
Drug Delivery Efficiency: Our tests assess the efficiency of drug delivery, ensuring the precise amount of medication is delivered to the patient with minimal wastage.
Customized Testing Protocols: Tailoring our services to your specific needs, we develop customized testing protocols that align with industry standards and regulatory requirements.
