Our Advanced Testing Capabilities
Particle Size Distribution Analysis: Using sophisticated methods, we measure the particle size distribution of aerosolized drugs delivered by nasal delivery devices. This analysis is crucial for ensuring optimal drug deposition in the lungs and effective treatment.
Nasal Drug Delivery Aerosol Testing: We evaluate the particle size and distribution to understand the devices performance in creating a aerosol that can reach targeted areas in the nasal-mucosal region.
Drug Delivery Efficiency: Our tests assess the efficiency of drug delivery, ensuring the maximum amount of medication is delivered to the patient with minimal wastage.
Customized Testing Protocols: Tailoring our services to your specific needs, we develop customized testing protocols that align with industry standards and regulatory requirements.
Testing Services Offered
We offer a wide array of testing services to help ensure that your device is effective and compliant with regulatory requirements. Some of our testing services include:
Delivered Dose Testing: We measure particle size distribution to determine the amount of drug delivered and its deposition in the nasal-mucosal area. Using pharmacopeia methods like cascade impaction and laser diffraction (with tools such as the Anderson Cascade Impactor and Next Generation Impactor), we ensure precise aerodynamic particle size distribution (APSD). High-performance liquid chromatography (HPLC) analysis further helps us optimize particle sizes for effective delivery.
Laser Diffraction Particle Size Analysis: This rapid screening tool is crucial for early-stage formulation development. Our advanced laser diffraction instruments, including Malvern Spraytec and TSI Aerodynamic Particle Sizers, accurately characterize particle size distribution, even for nano-particles (<500nm).
Nasal Product Stability and Device Compatibility: We evaluate device-material compatibility and stability, assessing potential degradation from materials used in device construction and ensuring consistent performance across the product's lifespan. Our testing spans various device types including multidose sprays, dry-powder devices, and nebulizers, and includes stability and accelerated aging studies.
Spray Pattern and Plume Geometry: Essential for regulatory compliance, particularly in the US and Europe, this testing assesses the shape, angle, and duration of the spray. We use automated instruments like the Proveris SprayView for actuation and high-speed imaging to ensure uniform drug delivery and bioavailability.
Why Choose ARE Labs for Nasal Drug Delivery Device Aerosol Testing?
Industry Expertise: With years of experience in aerosol science, our team brings an in-depth understanding of nasal drug delivery technology and respiratory drug delivery.
Cutting-Edge Technology: We employ the latest in aerosol testing equipment, ensuring precise and accurate results.
Regulatory Compliance: Our testing services are designed to help you navigate the regulatory landscape, ensuring your products comply with FDA, ISO, and other relevant standards.
Client-Centric Approach: We work closely with our clients, offering personalized service and expert guidance throughout the testing process.
Partner with Us
Explore our nasal drug delivery testing services and discover how ARE Labs can assist in optimizing your products for market success. Whether you're in the early stages of product development or preparing for regulatory submission, we provide the critical testing services you need.
