Other devices
Other devices which deliver medication or treatments to patients are emerging quickly. These new products aim to improve upon previous technologies such as traditional meter dose inhalers, nebulizers and nasal drug delivery devices. This may include devices such as:
Respimat Inhalers: Respimat is a brand of soft mist inhalers that deliver medication in a fine liquid mist. This device is designed to help patients who have difficulty using traditional MDIs or DPIs.
Adaptive Aerosol Delivery (AAD) Systems: These are sophisticated nebulizers that can adjust the timing and amount of medication delivery based on the patient's breathing pattern. This ensures more efficient drug delivery to the lungs.
Breath-Actuated Nebulizers (BAN): BANs release medication only when the patient inhales, which helps to reduce medication waste and ensures more medication is delivered to the lungs.
Hand-Held Atomizers: These devices are used primarily in ENT (ear, nose, throat) applications for local delivery of medications. They create a very fine spray that can be directed to specific areas in the nasal passages or throat.
Nasal Inhalers: These are designed specifically for administering medication into the nasal passages. They are commonly used for allergic rhinitis and other nasal conditions.
Smart Inhalers: These technologically advanced inhalers are equipped with sensors and digital tracking capabilities. They can monitor usage, remind patients to take their medication, and even collect data for healthcare providers.
Other Devices: There are many emerging technologies designed for aerosol drug delivery ARE Labs can assist in the testing and development of unique prototype devices that may not be listed above.
Our Advanced Testing Capabilities
Particle Size Distribution Analysis: Using sophisticated methods, we measure the particle size distribution of aerosolized drugs delivered by these medical devices. This analysis is crucial for ensuring optimal drug deposition in the lungs and effective treatment.
Droplet Aerosol Testing: We evaluate the droplet size and distribution to understand the device’s performance in creating a breathable aerosol that can reach the targeted areas in the respiratory tract.
Drug Delivery Efficiency: Our tests assess the efficiency of drug delivery, ensuring the maximum amount of medication is delivered to the patient with minimal wastage.
Customized Testing Protocols: Tailoring our services to your specific needs, we develop customized testing protocols that align with industry standards and regulatory requirements.
Testing Services Offered
We offer a wide array of testing services to help ensure that your device is effective and compliant with regulatory requirements. Some of our testing services include:
Delivered Dose Testing: ARE Labs excels in delivering API effectively to the lungs, specializing in producing aerosols under 5μm. By employing methods like cascade impaction and laser diffraction, alongside instruments like the Anderson Cascade Impactor (ACI) and Next Generation Impactor (NGI), we accurately measure the aerodynamic particle size distribution (APSD). With HPLC analysis, we ensure precise API concentration across particle sizes, optimizing them for inhalation in both nasal and inhaled products.
Laser Diffraction Particle Size Analysis: We offer rapid particle size analysis using advanced laser diffraction instruments, essential for early-stage drug formulation and device development. This method helps in understanding Mass Median Aerodynamic Diameter (MMAD), Geometric Standard Deviation (GSD), and overall particle size distribution. Our lab features cutting-edge technology including Malvern Spraytec and TSI Aerodynamic Particle Sizers, capable of analyzing nanoparticles under 500nm.
Spray Pattern and Plume Geometry Testing: ARE Labs conducts critical spray pattern and plume geometry assessments, mandated for release testing in U.S. and European markets. Evaluating the shape, angle, and duration of the spray, we determine its influence on drug delivery and bioavailability, crucial for nasal sprays and advanced inhalation technologies. Our use of the Proveris SprayView system allows for precise actuation and high-speed imaging, providing robust data essential for regulatory compliance and effective product performance.
Why Choose ARE Labs for Aerosol Drug Delivery Testing?
Industry Expertise: With years of experience in aerosol science, our team brings an in-depth understanding of nebulizer technology and respiratory drug delivery.
Cutting-Edge Technology: We employ the latest in aerosol testing equipment, ensuring precise and accurate results.
Regulatory Compliance: Our testing services are designed to help you navigate the regulatory landscape, ensuring your products comply with FDA, ISO, and other relevant standards.
Client-Centric Approach: We work closely with our clients, offering personalized service and expert guidance throughout the testing process.
Partner with Us:
Explore our nebulizer aerosol testing services and discover how ARE Labs can assist in optimizing your nebulizer products for market success. Whether you're in the early stages of product development or preparing for regulatory submission, we provide the critical testing services you need.