Advanced Processing Techniques for Dry Powder Formulations
Cutting-Edge Milling and Drying Processes: We employ advanced techniques like planetary ball milling and jet milling for fine-tuning particle sizes. Our spray drying and encapsulation methods, coupled with cyclone separation techniques, are meticulously executed to optimize the respirable mass of dry powder formulations.
Targeted Drug Deposition: Our processing expertise extends to achieving precise targeting of nasal mucosal/intra-nasal, upper, lower, and deep lung deposition sites, crucial for effective treatment outcomes in various respiratory conditions.
Utilizing Sophisticated Particle Engineering Strategies
Charge Masking and Particle Porosity Control: By implementing charge masking techniques and controlling particle porosity, we enhance the aerodynamic properties of particles, optimizing lung deposition and drug efficacy.
FDA-Approved Excipients for Drug Encapsulation: Our commitment to safety and compliance is evident in our use of FDA-approved lung excipients for drug encapsulation, ensuring the highest standards of quality and patient safety.
Comprehensive Particle Size Analysis and API Screening
Real-Time Laser Diffraction Particle Sizing: Utilizing real-time laser diffraction particle sizers, we provide immediate and precise analysis of Active Pharmaceutical Ingredients (API) formulations, ensuring optimal particle size distribution for effective inhalation delivery.
Cascade Impactor Testing for Verification: Our use of cascade impactors is integral to verifying the particle size distribution of drug formulations, an essential step in ensuring consistent and effective aerosol delivery.
Dry Powder Formulation Services
ARE Labs has extensive experience with a variety of different dry powder pharmaceutical formulations with different API’s, delivery methods and production techniques. Below are some of the formulation services we offer:
Dry Powder Inhaler (DPI) Formulation
Optimization of Existing Formulations
Dry Powder Inhaler Testing
Spray Drying Formulation
Encapsulation
Jet-milling and Grinding
Excipient Screening
Cyclone Separation
Packaging Options for Dry Powders
Regardless of your needs regarding dry-powder pharmaceuticals for inhalation ARE Labs has the experience and expertise to meet all of our clients needs.
Tailored Support in Aerosol Delivery and Packaging
Selection of Aerosol Delivery Devices: We guide you in choosing the most suitable aerosol delivery devices for your specific drug formulation, considering factors like patient usability and delivery efficiency.
Optimization of Packaging Solutions: ARE Labs offers expert assistance in packaging options, ensuring the stability and integrity of your drug formulation.
Characterization Testing for Dose Concentration Targeting: Our characterization testing services are designed to optimize your product for delivering the desired respired dose concentration, enhancing therapeutic effectiveness.
Tailored Solutions: At ARE Labs, we provide personalized solutions to meet the unique challenges of your drug formulation, from initial development to final product optimization.
Regulatory Compliance: Our commitment to using FDA-approved materials and rigorous testing methods ensures that your products meet all regulatory standards. We can assist you in getting your formulation to market and perform the FDA 510(k) testing required.
